I used to be an engineer with a government agency that worked on the GPS satellite constellation and I'm a bit of a GPS geek. My collection of GPS units is measured in dozens and range from gigantic "handhelds" the size of a laser printer which can calculate your position in a mere 55 minutes to the latest and greatest.
In my opinion, Garmin has always been the best in my experience. Trimble is better hardware, but they aren't a player in the consumer mapping GPS units.
I've had a few mis-routes with Garmin, but more with other brands and some (tom tom) have been so ridiculously bad they ended up in a garbage can at a gas station.
If you want a unit, I'd suggest Garmin. It does make me mad that the unit I bought specifically for the weather radar overlay is useless now because the data service that provided the weather info went under. It was nice having the graphics that show weather radar when traveling.
Currently I run a Passport IQ which is from Escort and has GPS and radar/laser detection all in one. The GPS is decent, but apparently Escort stopped making them and won't be making updates available.