Especially if they have a Chevy 1/2 ton 2000-2006 model 5.3L with a 4.10 gear-set ratio! My Tahoe is a 2 wheel drive 3.42 gear-set with 125,000 miles on it. I'm considering putting a re-manufactured rear end on it with a 4.10 gear-set ratio. I have had really good luck keeping machines running a long time (possibly because of a rigorous no beat-on-it philosophy). I'd venture to guess that the higher gear-set ratio would be in line with that philosophy.
There are threads discussing the above motor/gear-set combination so I have a fairly good idea what to expect, so much good information on the forums! I'll probably be hauling my trailer with the same Tahoe 15 years from now (seriously).