We ran ours all the time on our previous unit. Never had a problem. The owners manual even had directions for doing so, and there was a gen start button located in the drivers area cluster of switches.
Our previous motorhome was a class A Airstream Land Yacht. Had two roof airs and required 50 amp sevice. The generator would run both air conditioners and anything else that was wanted at the same time, no problems.
Our current unit has not been run while we drive, but I would not hesitate to run it if I needed it.
Me, my wife & our son.
2014 Jayco Redhawk 26xs bought new in April 2014.
Camping, Fishing, Blue Grass, Video & Computer Games