Probably not. It's an impression left over from the banding of tires into a stack while they are still hot, and seems to have no effect whatsoever on the performance or life of a tire.
Have them on 2 of our 3 vehicles. Friend owns a tire shop and he would never let me drive with something unsafe.
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2019 Chevy express 2500 Van Coversion. 2017 Jayco 23MRB: 26' total and Glacier Package. 2 Renogy solar panels. Married 49 years. Haley the mutt, 4 years old. "Excited to learn new things everyday and humbled by those who offer to help." And very grateful to our Moderators!