I mix up water, a couple tablespoons Clorox bleach, and about 1/4 tsp of Dawn dish detergent in a spray bottle (old Formula 409 bottle). I spray the bowl interior with it almost after every flush. Toilet stays really clean.
I've used this for two or three years, with no negative effect on the bowl seal.
2011 Dodge Ram 1500 HEMI Quad Cab
2011 Jay Flight 26BH