There are some long runs of 6% grade going up, and going down. We did 14 this last summer, and while steep, twisty, and in some spots the turns were posted at 15 mph, we had no issues. The Bighorns are one of my favorite places to go, although we don't do it very often.
It can be a bit tight in the established campgrounds to get a spot, especially on weekends. There is a wealth of boondocking space off the roads.
I was strongly advised NOT to try taking Hwy 14A when pulling a trailer. But 14 or 16 are just fine!
2012 Ford F-150 Eco, SCrew, 4x4, MaxTow, HD Payload
SOB, used to be:Jayco 26.5 RLS