It's a somewhat personal decision IMHO. Personally, I would go with a Super C.
A significant reason for that involves safety (which is one of the reasons I went with a Class C as opposed to an A when I was choosing my current rig). With a Super C, you have a real chassis out in front of you with crumple zones, and potentially air bags as well. In a Class A, you have fiberglass, glass, maybe a little metal. In a front-end collision, I would take the safety attributes of a Super C over an A every day of the week and twice on Sunday.
Then there's the hauling and towing capacity variance. Super C is going to have A LOT more towing and cargo capacity than a gas Class A (not talking about a pusher, that's a whole different ball of wax).
Also, most Super C chassis these days are equipped with a diesel engine, which is a nice advantage in a lot of circumstances. It also has its disadvantages though. This somewhat depends on how much you will use it, and what you'll use it for, and where you'll use it. Going through the mountains, I'd choose a diesel Super C over a class A. Using quite frequently (not sitting in storage as much), I put the advantage to Super C. Towing a trailer or heavy toad; advantage Super C.
Super C rigs tend to handle better than Class A rigs "out of the gate". You can modify and improve Class A chassis to handle well, but the Super C is "more" ready to go right when you pick it up.
And there are floor plan considerations as well.
Personally, I intend for our current Ford chassis Class C to last us until we purchase our "retirement" rig. If I were shopping that rig today, my 2 categories would be Super C or 5th wheel towed by a diesel truck. We intend to use the HECK out of our RV in retirement. But that's 15 years away, so who knows what the world will look like then...
If budget had allowed, I'd have been in a Super C 3 years ago when we purchased our Greyhawk.
-2018 Greyhawk 29MV
-2020 Jeep Wrangler Unlimited (JLU) (Primary Toad)
-1994 Jeep Wrangler YJ (Secondary Toad)
-2014 Jay Flight 28BHBE & Ram 2500 6.4L CC 4x4 (sold)