I hadn't thought about the child safety seats, either. But I don't have any little ones, so it wasn't ever in the equation. For me, it came down to three things:
1)
Two Drive Trains - I'm not mechanically inclined, so I didn't want to have to deal with the maintenance and expense of two drive trains. And if you have to take your motor home in for extended drive train service, you're without a house for however long it takes.
2)
Daily Driver Requirements While Camping - I do a lot of fishing, hunting, and hauling while camping, so I need a vehicle to accommodate all of my gear and game. While a small AWD vehicle might serve most of your daily driving needs, try hauling a deer in one!
3)
Travel Noise - Things you store in your RV (like pots & pans, dishes, flatware, refrigerated items, even the oven door & cooktop grates) tend to bounce around and rattle while you travel down the road. That can be very annoying to some people. In a motor home, it's just something you have to put up with. In a pull-behind, it's not even an issue.
For those reasons,
I selected a truck and travel trailer. Your choice will depend on your needs and wants. I've always said, "You can either drive your car and pull your house, or you can drive your house and pull your car." The choice is up to you. Whichever choice you make, the most important thing is to enjoy it!