Those stock radio units for the Ford E series vans are similar or maybe exact radios used in the F-series trucks or Excursions. A double DIN unit could fit in that rectangular opening, but may need to trim off 1/8" lip on the top of that opening. A double DIN kit and wiring harnesses would be needed.
Double DIN kit
https://a.co/d/adiTrFJ
Wiring harness
https://a.co/d/1cfXLoa
You have a wide choice of which radio to go with. I have this Android unit on my other vehicle and it connects Android Auto or Apple Carplay wirelessly.
https://a.co/d/hi1oG0h
You can also connect via USB type A, but what I find is that it doesn't charge my Samsung phone well. Connecting wirelessly and using your phone's cable to the cigarette light to charge would work best.
Not sure if you currently have an aftermarket radio already installed, but if you do, you may already have the double DIN kit you could reuse.
I install my own car radios for years so I know what it entails. It's pretty simple. I don't know what a shop would charge to install, but at least the above could give you ideas on the cost of the hardware and equipment.
Good luck.