Initially just hand tighten "snug'", turn on the water check for leaks, and tighten slightly further by hand if required.
The plastic connectors on the PEX lines have a rubber 'cone seal' within them and are basically good for a single tightening application....., additional disconnect/reconnects are just borrowed time before a leak starts. Many problems start at the factory because they are overtightened and damage the cone seal.
RV dealership sell cone seals for these connections and I always keep a few on hand.
My factory damaged cone seal at the toilet connection, and the new cone seal.
New cone seal in place:
Bob
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2016 GM 2500HD 6.0L/4.10
2018 Jay Flight 24RBS
2002 GM 2500HD 6.0L/4:10 (retired)
2005 Jayco Eagle 278FBS (retired)
1999 Jayco Eagle 246FB (retired)
Reese HP Dual Cam (Strait-Line)