Sorry for the long post.
Well, we are about to go from FT to a stick house again. Whether or not you enjoy it depends a lot on why you are doing it and what you expect it to be like. Are you recently retired? Kids recently moved away. Any 'extra' major life changes will complicate the situation.
Our 'adventure' was mostly to see where in the country we wanted to live and that was accomplished after a 18 months. We thought it would take a lot longer but having the fifth wheel made the decision easier as we could live in the prospective areas for a while to see what they were really like.
Before you go, have you ever lived in very close quarters with your wife for long periods of time? It will aggravate any 'discrepancies' that you two have with each other. It is more difficult to have separate quiet time/lives. What do you do in your free time and will the trailer support it. We selected a bunkhouse model so we could still pursue our hobbies. It was still not that easy since only one of us could be in there at a time. The floorplan is probably the MOST important part of choosing an RV. If it is not right you will come to resent the small things. We went through that with a prior RV.
You will also find out a lot about yourself and each other and you will pobably change a bit as you go along. Be prepared for some very emotional times.
Cost. It is not as inexpensive as you might think depending on where you choose to park. Daily rates, especially near popular locations, will be in the $50/day range, and can be higher. Monthly rates are quite a bit less, but, some RV parks have limited monthly rate spots. Our son lives in Seattle area. Only three RV sites nearby. One has no monthly sites and the other two are full (full time residents). Cost for us to stay in that area is about $1500/month. Don't get me wrong, if you are careful you can get by for a lot less if you are willing to stay in the less expensive parks. And, if you boondock stays are 'free'.
If you do plan to boondock I highly recommend a genset installed in the RV, sized to run at least two AC units.
Pros: You can travel whenever you want and stay in any area you want as long as you want. You can 'live' in many places where you probably could not afford to live in an apt or stick house. For someone who likes to see the sights it is an ideal lifestyle.
Cons: A lot depends on your hobbies and interests. Some hobbies are incompatible or difficult with a mobile lifestyle.
One hazard is internet service. If you require very high speed then it will be costly or even impossible. Regular surfing and such is doable with just a cell phone connection. Large documents or streaming of video is limited.
If you need good TV service then budget in a good satellite ant and service.
Flooplan. Choose one that suits your interests.
Travel. The larger the RV, the more difficult it is to travel. When we started we thought, 'we can finally stop at all those small towns we used to pass.' Well, that didn't quite happen. Most of those small towns had not parking area big enough for our rig and no campground or RV park to stay in. So drive down the road and not find anyplace for over an hour. Yes, you can stay somewhere and then drive around to sightsee. Our life was complicated by our dog so that created another issue to deal with when going out for the day.
We also thought we might do some old fashioned camping. The length of the rig made that very difficlt. Not very many places where we could drag a 35ft 11,000lb trailer. The old saying is, the bigger the rig, the less 'camping' you do. For us 35ft meant no more 'camping' (I define camping as not being in a full hookup site).
Planning. Larger rigs do not fit in many gas stations. If you have a diesel rig then plan on using truck stop pumps (or the Flying J RV islands). We also thought that most rural areas would have diesel pumps. Not always true. We found that many rural areas in the SE would not have very many diesel pumps that we could put the rig into. Then there are the roads themselves. Longer rigs mean being a bit careful about where you go. There are many 'traps' where you cannot turn around. At first I found the plannning a challenge and part of the life. Now I find it a PITA and it affected my enjoyment of the trip.
Last. Vacation. Basically this is a positive and negative. When you go you have all your own stuff with you and your own bed. On the neg side, even on vacation you are still at 'home'. Can't explain it much better. We solved the problem by going to hotels every now and then for a getaway. It meant finding a kennel for the dog, but, at least we felt like we were on vacation. Adds a lot to the cost of the lifestyle.