As long as the forecast doesn't call for under 32 degrees for several hours why not. It takes a while to freeze and low temps to do it.
But alternatively, a sudden change and all you would need to do is get out the compressor and run 40 psi through all the pipes and faucets. Less than 20 minutes for me, takes longer fro the fresh water tank to drain if it was full.
I also do it with a dollop of pink in each drain.
An additional task if fall is to go back a few hours later and re run the blowout in case water settled in a line some where but I just leave the compressor set up and go out later in the same day so no extra work.