I have agonized with several solar setups on three travel trailers. When the larger capacities were not available in one panel at a moderate cost I have gone with multiple 100 watt panels. For a camper of your size i would personally make every effort to create a compact setup on the roof, which does minimize your holes in your roof.
But before I would do any solar install, go ahead and clean your roof and treat it with good silicone treatment, which will treat the areas under where the solar panels will be located, which you will not be able to do after you install your solar.
While Renogy offers package prices using their 100 watt panels, which may sound like a deal, try to avoid going the four panel setup, IMHO. I used Rich on my current camper and I am not sure if there is a dimes worth of difference in the panels from the two outlets.