I'll agree with the others and say that they do help some.
But I'll add something: that is not really their purpose. Where they REALLY shine is in the "wallowing", especially during turns at slow speeds. You go from thinking you're going to roll the whole works before install, to a nice, controlled, relatively flat turn after they're in.
Really, the best thing you can do for what you're experiencing is get Caster adjusted to at least ~5.5.
Upgrading the front sway bar helps too, as does upgrading the steering damper. But all these things are not a direct fix.
Standard upgrade/mod list for the Ford E450 Chassis:
-Increase Caster. You will need to find a shop willing to install the required adjustment sleeves to achieve ~5.5 degrees. The way it's set from Ford is "within spec" for the chassis, so the shop needs to be willing to listen to you, and it's best if they have experience with it.
-Tighten rear helper springs (they are usually just "installed" and not adjusted properly)
-Upgrade front sway bar (Ford OEM is a piece of junk)
-Upgrade front steering damper
-Upgrade front bump stops; Sumo or other
-Install rear trac bar
-Upgrade front/rear shocks
You do all of that, and it's likely to drive like a Suburban. Maybe an older one, but still a LOT better than how it comes off the lot. Plus that's about everything you can do that I know of.