I would wait to drain the water out of the fresh water tank, until after winterizing so you can make sure there is no air in the lines(only water) when you start pumping the antifreeze.
These are the instructions I found to winterize the Nautilus P3 control system from the Nautilus mfg web site (see link below)
Nautilus Panel Winterize Troubleshooting Steps
Steps to follow before submitting any type of claim due to not winterizing;
1.Disconnect hose.
2. Make sure all low point drains are closed.
3. Open a cold faucet to relieve system pressure and leave open.
4. Throw all handles in the opposite direction of winterize and then put them back in the winterize position.
5. If there is a water filter on the outside of unit, fill filter with winterize solution and make sure lid is tightly sealed so air
can’t get through.
6. Remove screen washer from City Water inlet and turn it around so cone is facing towards Nautilus panel and put it
back into water inlet. NOTE: When winterizing is finished, return screen washer to original position.
7. Make sure the hose being used is less than 3 feet long.
8. Connect short hose to the City Water inlet on Nautilus panel making sure you have a tight connection that will not
allow air to enter the inlet.
9. Place bottle or bucket of winterizing solution level with or above the inlet on the Nautilus panel so the fluid is not
fighting gravity.
10. Place free end of short hose in winterizing solution.
11. Turn on pump switch.
12. Winterizing fluid should be flowing into the Nautilus panel.
13. When finished winterizing, disconnect hose from Nautilus panel.
15. if problems persist with winterizing, contact your dealer or the RV manufacuterer.
Here is a link to several of the Naulitus wet bay systems, click on the one you have and there is a lot of info.
https://www.bandbmolders.com/index.php/nautilus/