We did it in 2015 in our X23B hybrid, left home 3 weeks after retiring at the end of April.
Previous posts have lots of good advice. We traveled from Pennsylvania, took almost 4 months, put 15,500 miles on the truck. Had NO tire issues, but did lose our brakes at one point due to the brake wire hanging low and getting ripped off. Roads are mostly as good as the lower 48. We spent over a month in AK. Loved the Kenai peninsula area best, and hope to get back there in another year or so.
What's your rig?
2019 Jayco Eagle HT 30.5 MBOK
2019 Ford F-250 King Ranch diesel
2015 Jayco X23B (sold)
2008 Jayco 23B (sold)
2010 Ford F-150 King Ranch (sold)