Plugging the holes on the Mirror mounts on the doors quiets the noise down dramatically. I had read about this before we picked ours up and took Gorilla tape with me. We left the dealer late and I didnt bother with it but after a bit on the Highway we pulled into the first rest stop we came across and put tape on the holes
I also checked my door seals with the doors shut on a piece of paper and there are several spots the seal isn't even touching the door and can slide paper in and out. There are many posts about this if you search and many people are having the doors readjusted at Freightliner under warranty which I will be checking into.
The high frequency whine can be from the nav system. There have been many fixes posted but the only one that worked for me is to unplug the Yellow Video cable that runs to the TV. Some have unplugged by taking dash apart but I just unplugged it from the TV on the back and the whine was completely gone.