I went through this a few years ago with the 5th wheel we had prior to our motorhome. We needed to replace four slide toppers and the main awning. We went with a heavy duty vinyl from
www.toughtopawnings.com. We were very happy with the product and the material was far superior to the 'stock' material.
Now, why did we choose vinyl and not acrylic. The acrylic look to me like a 'sheet' product and felt more rubbery than vinyl. Because of its 'sheet' style it seemed like it could get more brittle over time and temp changes and that if a rip or tear started somewhere that it would likely 'run' all the way up or across. The vinyl on the otherhand looked almost like it was MFG'd similar to ripstop material, where if there was an issue it would be isolated by the materials structure. As it was also more fabric like than rubber like I felt that it would be more resistant to the elements. Like I said we were happy with it.
If you do choose to go vinyl I couldn't recommend a better place than Tough Top. We followed their measuring instructions and the product was perfectly cut. Their customer support was also top notch and they provided a ton of guidnace for installation.
Whatever you choose, best of luck with the replacement.